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What Forests Could Hold for the Future of Cancer Treatment

Cancer treatment has benefited from plant-derived compounds, including medicines used against leukaemia, lymphoma, breast and ovarian cancers. But deforestation could destroy plants that may contain compounds with potential for future drug discovery.

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Cancer treatment and the search for new plant-derived medicines
Cancer treatment has benefited from medicines derived from natural compounds, including those found in plants. Representational image. Image credit: Ivan S/Pexels

Cancer remains one of the biggest challenges in medicine. While treatments have improved significantly, there is no single cure for cancer, and some cancers remain difficult to treat. Researchers continue to look for drugs that can target cancer cells more effectively and overcome treatment resistance.

cancer treatment medicines used today were developed from compounds found in plants. Researchers are still studying plants for molecules that could be developed into new drugs. But deforestation could reduce the number of species available for this research, a new analysis suggests.

An analysis by Zero Carbon Analytics estimates that tropical forests contain about USD 714 billion in potential commercial pharmaceutical discovery value from flowering plants. It estimates that deforestation between 2001 and 2024 has already put about USD 86 billion of this potential value at risk. The finding is relevant to cancer research because natural products have contributed to several cancer medicines.

Cancer Medicines From Plants

The link between forests and cancer treatment is already well established. Vincristine and vinblastine, derived from the Madagascar periwinkle, are used against leukaemia, lymphoma and other cancers. Paclitaxel, first isolated from the Pacific yew, is used to treat cancers including breast and ovarian cancer. Camptothecin, from Camptotheca acuminata, led to the development of the cancer drugs irinotecan and topotecan.

Their contribution is part of a wider pattern. A review found that about 25% of anticancer drugs approved between 1981 and 2019 were related to natural products. Zero Carbon Analytics reports that three in four cancer drugs discovered between 1940 and 2014 were natural products, derived from them or inspired by them.

The Research Gap

The bigger concern is what forests could still offer cancer treatment research in the future. The analysis calls this “option value” — the value of keeping open the possibility of discovering new medicines from plants that have not yet been studied.

That possibility is large. The analysis estimates that 99% of plant compounds remain unexplored and that tropical forests could contain around 328 plant-derived drugs with potential commercial value, although the estimate ranges from 200 to 460.

These are not 328 ready-made cancer drugs. Most compounds found in plants will not become medicines and must first go through laboratory tests, safety checks and clinical trials.

Cancer treatment research using plant-derived compounds from forest species
Cancer treatment research includes studying forest plants for potential medicinal compounds. Representational image. Image credit: iStock

But once a species is lost before scientists study it, that opportunity may be lost too. For cancer research, deforestation could therefore mean losing potential sources of new cancer treatments before researchers know what they contain.

What This Means For The Western Ghats?

India’s Western Ghats shows how much remains to be studied. A 2025 review recorded 1,628 medicinal plant species used traditionally in the region, but only 115 had been validated through scientific studies or clinical use.

Some are already being tested for possible cancer-related properties. A 2025 study of Tarenna alpestris, a plant from the Megamalai Hills, found anticancer activity against colon cancer cells in the laboratory.

This does not mean the plant can treat cancer. More research is needed to identify the active compounds and test their safety and effectiveness. But it shows how plants can enter the early stages of cancer-drug research.

Why Forest Loss Matters To This Research

Deforestation can remove species before researchers have a chance to study them. The Zero Carbon Analytics analysis estimates that continued deforestation could put USD 174 billion in potential pharmaceutical value at risk by 2050. Stopping deforestation by 2030 could preserve about USD 79 billion of that potential value.

These figures are about possible drug discoveries, not confirmed cancer treatments. For cancer research, the concern is simpler: losing forests could mean losing plants and compounds that might lead to new anticancer drugs.

Technology can help scientists study natural compounds, but it cannot replace species or compounds that were never studied. Natural products are only one part of cancer-drug research, but the history of vincristine, vinblastine, paclitaxel and camptothecin shows that they have already contributed to cancer treatment. The question is how much potential could be lost before researchers get the chance to study it.

 

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Deforestation Could Erase the Biological Library Behind Future Medicines

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Tropical forest threatened by deforestation and biodiversity loss
Tropical forests hold biodiversity that could provide compounds for future medicines, but deforestation puts this potential at risk. Representational image. Image credit: Kati Lenart/Pexels

When we think of deforestation, we often think of lost habitats, disappearing wildlife and declining biodiversity. For the pharmaceutical industry, a forest is a vast biological library. Plants, fungi, microbes and animals produce chemical compounds to survive, some of which can be useful in treating human disease. Scientists can use these natural compounds directly as medicines or as starting points for developing new drugs.

This makes biodiversity an important resource for pharmaceutical research, particularly in tropical forests. According to a new report by Zero Carbon Analytics, 56 of the 579 new drugs approved globally between 2014 and 2024 were natural products or close derivatives.

Yet scientists have explored only a fraction of nature’s chemical diversity. Around 99% of plant compounds are still estimated to be undiscovered, leaving tropical forests as a vast, largely untapped source of potential medicines.

Forests are a Natural Drug-Discovery Library

Plants produce chemical compounds to defend themselves against pests, disease and harsh environments. Some of these compounds can also have medicinal properties.

Vincristine, for example, comes from the Madagascar periwinkle and remains on the WHO List of Essential Medicines. It has been widely used to treat childhood leukaemia, with no full replacement yet available.

Scientist examining a plant sample in a laboratory for potential medical research
Scientists study plant compounds in laboratories to identify natural substances that could contribute to future drug discovery. Representational image. Image credit: Mehul Patel/Pexels

This means forests are valuable for the species scientists have yet to study. Every species could hold compounds that become important to future medicine.

What Happens When Forests Disappear?

When forests are cleared, scientists can lose access to plants and other organisms before their potential is ever studied. The chemical and genetic information they contain can disappear with their habitat. Researchers describe this as losing an “option value” — the opportunity to discover and develop medicines in the future. Once a forest is gone, that opportunity may disappear with it.

This does not mean every species lost would have produced a major drug. The study measures potential future discoveries, not guaranteed medicines. But that uncertainty is precisely the problem: scientists cannot know what they have lost if they never get the chance to study it. The new analysis estimates that tropical forests could contain around $714 billion in potential commercial pharmaceutical value from undiscovered drugs in flowering plants alone. Their broader social value could be around $7 trillion.

Deforestation is already reducing this potential. Since 2001, forest loss is estimated to have put about $86 billion in potential drug-discovery value at risk.

The Risk Extends to Future Medicines

The threat does not stop with what has already been lost. Around 13% of the world’s tropical forests have been affected by forest loss since 2001, according to satellite data cited in the study. If deforestation continues at current rates, another $88 billion in potential commercial pharmaceutical value could be put at risk by 2050. The cumulative value at risk since 2001 could reach $174 billion, with the upper estimate reaching $287 billion.

Halting deforestation could preserve much of this potential. If forest loss were stopped by 2030, the researchers estimate that $79 billion in commercial pharmaceutical value could be preserved by 2050 compared with business as usual.

The social stakes are even larger. Under business as usual, another $880 billion in social value from potential medicines could be lost by 2050.

Technology Cannot Replace a Forest

AI, genomics and digital sequence information are helping scientists search nature’s biological library faster. Genetic data can reveal promising biological pathways, while AI can help researchers analyse huge genomic and chemical databases. But these technologies still depend on biological information originating in nature.

Once a species is lost before its genetic information is recorded, technology cannot recover it. This also raises equity questions: tropical forests are in the Global South, while most pharmaceutical profits flow to companies in wealthier countries. Indigenous communities have long contributed knowledge of medicinal plants but receive little of the financial returns.

Protecting forests, therefore, is not only about conserving biodiversity. It could also mean protecting the biological foundation of future drug discovery.

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India Beat Hunger. Now It Has to Make Healthy Food Affordable

India has significantly reduced hunger through its food security programmes, but more than 520 million people still cannot afford a healthy diet. As food prices rise and nutrition gaps persist, India’s next challenge is ensuring that every family can access balanced, affordable meals.

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Child and adult hands holding a bowl of rice, symbolising India's food security efforts and the challenge of accessing nutritious diets.
A bowl of subsidised rice represents India's success in reducing hunger, while millions still struggle to afford diverse and nutritious diets beyond staple cereals. Representational image. Image credits: Ian Taylor/ Pexels

India has largely beaten hunger, but food security now faces a new test. A new UN report finds that while fewer people are undernourished, the high cost of healthy diets continues to keep nutritious food out of reach for millions.

Every month, nearly 800 million Indians collect subsidized rice and wheat from ration shops through the Public Distribution System (PDS). For millions of families, these grains ensure that no one sleeps hungry and ensure food security. It is one of the country’s biggest social protection programs and a key reason why hunger has steadily declined over the years. But as India wins one battle on food security, another is becoming harder to ignore.

The State of Food Security and Nutrition in the World (SOFI) 2026 report, released by the UN’s food and health agencies on 21 July, estimates that more than 520 million Indians cannot afford a healthy diet. More than one in every three people may have enough calories to get through the day but still struggle to regularly buy fruits, vegetables, pulses, milk, eggs and other nutrient-rich foods.

The contrast reveals a shift in India’s food security challenge. Hunger is no longer the country’s biggest concern. Nutrition is.

Food Security: India Solved the Problem of Empty Stomachs

India’s food security system was designed to tackle famine and chronic food shortages. The Green Revolution transformed cereal production, while government procurement and subsidised food distribution made rice and wheat accessible to poor households. During the Covid-19 pandemic, free food grain distribution further strengthened this safety net, protecting millions from falling into extreme hunger, ensured food security.

The strategy has worked. According to SOFI 2026, the prevalence of undernourishment in India has fallen from 21.1% in 2004-06 to 9.8% in 2023-25, a decline of roughly 101 million people, from 243.9 million to 142.5 million. Fewer Indians today are unable to consume the minimum calories required for a healthy life. For decades, this was the country’s biggest food security challenge.

Why Healthy Food Remains Out of Reach

Calories have become relatively affordable, while nutrition has become expensive. For many families, buying rice is rarely the problem. Buying milk every day, eggs for children or enough vegetables through the week often is. The imbalance is reflected not only in food prices but also in what Indians eat.

A study comparing Indian diets with the EAT-Lancet healthy diet found that among the poorest rural households, cereals provide around 70% of daily calories. By contrast, protein-rich foods contribute only 6-8% of total calories, far below the 29% recommended under the EAT-Lancet healthy diet. Even the richest Indian households consume fewer fruits, vegetables and non-cereal protein sources than recommended.

The affordability gap widens further when food prices rise. The share of Indians unable to afford a healthy diet has fallen sharply, from 59.8% in 2017 to 35.5% in 2025 — but SOFI 2026 puts the cost of that diet at US$4.11 per person per day (PPP) in 2025. Globally, the cost of a healthy diet has climbed from US$2.94 in 2017 to US$4.28 in 2025, an increase of roughly 45%.

Research published in the journal Food Policy paints a similar picture. It found that rural Indians typically spend only about US$1 per person per day on food, while a healthy diet costs between US$3 and US$5 per person per day. Much of that gap comes from the higher cost of fruits, dairy products and protein-rich foods.

Raj Patel, professor at the University of Texas at Austin and an expert with the International Panel of Experts on Sustainable Food Systems (IPES-Food), says this imbalance is rooted in the way food systems are organised.

“When 645 million people are hungry and one in three cannot afford a healthy diet, this is a failure of political choices. Healthy diets are becoming a luxury for billions, while farmers are paid less and consumers pay more. That isn’t an accident — it’s the result of a food system where a handful of powerful traders, processors and retailers set the prices and pocket the profits.”

His observation resonates in India, where cereals remain affordable through public support, while nutritious foods often become the first items families stop buying when household budgets tighten.

A Full Stomach Does Not Always Mean Good Nutrition

For decades, food security has largely been understood as having enough food on the plate.

According to neurologist Dr Arun Oommen, representative to the United Nations Economic and Social Council (ECOSOC), that understanding needs to evolve.

“The biggest misconception in India is that people think if their stomach is full, there is no malnutrition. People eat what is cheaply available, but those foods often lack the proteins, vitamins and minerals needed by the body.”, he told EdPublica

He says the pattern is especially common among low-income households, where meals are built around rice, with only small portions of vegetables or protein-rich foods.

An Indian street food stall displaying pulses, sprouts, legumes and other nutritious foods, highlighting the importance of diverse diets for food security and nutrition.
Despite reducing hunger, many Indians still rely on carbohydrate-rich diets, with nutritious foods remaining less affordable. Representational image. Image credit: NEOSiAM 2026+/Pexels

“Without adequate proteins, vitamins and minerals, the brain, muscles and other organs cannot develop properly. Many low-income families depend largely on carbohydrate-rich diets, with large portions of rice and very little protein or vegetables.”

The effects are often hidden. Children may get enough calories to avoid hunger but still miss out on the nutrients needed for healthy growth and brain development.

The Hidden Face of Malnutrition

The consequences are visible in India’s nutrition indicators. SOFI 2026 records that child stunting has fallen from 41.7% in 2012 to 32.9% in 2024 (from 53.3 million to 37.4 million children) — real progress, but still meaning more than one in three Indian children under five have low height for their age. Wasting stood at 18.7% (22.2 million children) in 2024, and anaemia among women aged 15-49 has risen from 50.1% in 2012 to 53.7% in 2023, now affecting 203.5 million women. These are signs not simply of inadequate food, but of diets that lack diversity.

This is where India’s food security story enters a new phase. Rice and wheat remain essential because they protect people from hunger. But they cannot, on their own, provide the balanced nutrition needed for healthy lives. As food inflation, climate change and disruptions to agricultural production continue to push up the prices of fruits, vegetables and pulses, nutritious diets become even harder to afford.

Jennifer Clapp, Canada Research Chair at the University of Waterloo and an IPES-Food expert, warns that global food systems face growing uncertainty.

“Global hunger remains stubbornly high. And the outlook for 2026 is deeply worrying. Geopolitics is increasingly shaping food security, with conflict, fertiliser disruptions, trade tensions, and El Niño-driven climate shocks threatening yet another surge in food prices.”

For India, another round of food price increases could widen the gap between escaping hunger and eating well.

The Next Step in India’s Food Security Journey

India has shown that large-scale public policy can reduce hunger. Few countries have built a food distribution system that reaches hundreds of millions of people every month. The next challenge is making healthy food just as accessible as cereals.

As Dr Oommen puts it: “Rice and wheat are important, but relying on them alone can create nutritional deficiencies. People need to include more vegetables, fruits and protein-rich foods in their diet.”

India’s food security story is no longer only about ensuring that people have enough to eat. It is about ensuring they can afford to eat well. The country’s next measure of success may not be how many empty stomachs it eliminates, but how many families can finally put a balanced, nutritious meal on the table.

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Ebola Outbreak Could Push Nearly One Million More People into Poverty, Cost Africa Billions: UNDP

While the immediate focus remains on containing the virus, the UNDP says the outbreak is also threatening livelihoods, jobs and public services, particularly in countries with fragile health systems

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An Ebola screening checkpoint at a roadside in an African community during an Ebola outbreak.
An Ebola screening checkpoint set up to monitor and prevent the spread of the virus in an affected community. Image credit: harry1978/iStock

The ongoing Ebola outbreak in the Democratic Republic of the Congo (DRC) could push nearly one million more people into poverty and wipe billions of dollars from Africa’s economy if it is not contained quickly, according to a new analysis by the United Nations Development Program (UNDP).

While the immediate focus remains on containing the virus, the UNDP says the outbreak is also threatening livelihoods, jobs and public services, particularly in countries with fragile health systems. It warns that the economic effects are likely to outlast the health emergency, with women expected to face the greatest impact.

The analysis estimates that the outbreak could push an additional 985,000 people below the poverty line across Africa. In the worst-case scenario, the continent could lose up to US$3.6 billion as trade slows, businesses are disrupted and governments divert resources to emergency response.

“The cost of Ebola is measured not only in lives lost, but also in livelihoods lost,” the report notes, arguing that outbreaks of infectious diseases can undo years of development progress in a matter of months.

Women Likely to Bear the Brunt

According to the report, women are likely to be affected disproportionately because they make up much of the informal workforce and are often the primary caregivers at home. Restrictions on movement and market closures can cut off income for women working in informal trade, while increased caregiving responsibilities further reduce their economic opportunities.

The report also warns that pressure on healthcare systems could interrupt routine maternal and child health services, creating additional health risks beyond Ebola itself.

Economic Disruption Extends Beyond Affected Countries

Even if the outbreak remains concentrated in the DRC and neighbouring countries, its economic effects are expected to spread more widely through reduced trade, lower investor confidence and disruptions to regional supply chains.

The UNDP estimates that the DRC alone could lose more than US$1 billion in economic output and tens of thousands of jobs. Across the continent, the losses could reach US$2.37 billion under a moderate scenario and as much as US$3.6 billion if the outbreak spreads further.

Ebola Outbreak: A call for a Broader Response

The agency says responding to Ebola requires more than medical interventions. Along with strengthening surveillance and healthcare systems, governments should protect livelihoods through social safety nets, maintain essential public services and ensure that border measures do not unnecessarily disrupt trade.

According to the report, addressing these wider social and economic impacts will be crucial to preventing the current Ebola outbreak from becoming a long-term development setback for the region.

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