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Researchers develop AI algorithm to accurately detect heart murmurs in dogs

Researchers have developed AI Algorithm to detect heart murmurs in dogs, improving early diagnosis of cardiac disease

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Tutty Dog
Tutty, a Miniature Pinscher, is one of the popular small breeds known for its vibrant personality. Image credit: DD/EdPublica

Researchers at the University of Cambridge have developed a machine learning algorithm capable of accurately detecting heart murmurs in dogs—a critical indicator of cardiac disease, particularly prevalent in smaller breeds like the King Charles Spaniel. This innovative approach has the potential to transform veterinary care, offering an accessible tool for early diagnosis and treatment of heart conditions.

Heart murmurs are a key sign of mitral valve disease, the most common heart issue affecting adult dogs. Statistically, approximately one in every 30 dogs seen by a veterinarian presents with a heart murmur, with higher rates observed in small breeds and older dogs. Given the frequency of such conditions, timely detection is essential. Early intervention can significantly enhance a dog’s quality of life and longevity, making effective screening methods vital for veterinarians.

Dr. Andrew McDonald, the study’s first author from the Department of Engineering at Cambridge, emphasized the importance of early detection, according to a statement issued by the University: “Heart disease in humans is a huge health issue, but in dogs it’s an even bigger problem. Most smaller dog breeds will have heart disease when they get older, but obviously dogs can’t communicate in the same way that humans can, so it’s up to primary care vets to detect heart disease early enough so it can be treated.”

The Algorithm’s Development

The research team began with an algorithm initially designed for human heart sound analysis. Recognizing the similarities between mammalian heart function, they adapted this technology to analyze audio recordings from digital stethoscopes used on dogs. The algorithm demonstrated an impressive sensitivity of 90% in detecting heart murmurs, a level of accuracy comparable to that of expert cardiologists.

Professor Anurag Agarwal, the lead researcher and an expert in acoustics and bioengineering, noted the absence of a dedicated database for canine heart sounds. “As far as we’re aware, there are no existing databases of heart sounds in dogs, which is why we started out with a database of heart sounds in humans,” he explained in a statement issued by the University of Cambridge. “Mammalian hearts are fairly similar, and when things go wrong, they tend to go wrong in similar ways.”

The team refined the algorithm to not only detect but also grade heart murmurs

To build a robust dataset, the researchers collected heart sound data from nearly 800 dogs undergoing routine examinations at four veterinary specialist centers across the UK. Each dog received a thorough physical examination and an echocardiogram performed by a cardiologist, who graded any detected murmurs and identified underlying cardiac issues. This effort resulted in the largest dataset of dog heart sounds ever compiled.

Expanding the Dataset for Better Outcomes

Co-author Professor Jose Novo Matos, a small animal cardiology specialist, highlighted the need for diverse data to improve the algorithm’s effectiveness: “Mitral valve disease mainly affects smaller dogs, but to test and improve our algorithm, we wanted to get data from dogs of all shapes, sizes, and ages. The more data we have to train it, the more useful our algorithm will be, both for vets and for dog owners.”

The team refined the algorithm to not only detect but also grade heart murmurs, distinguishing between mild and advanced disease requiring further intervention. This innovation aims to empower general veterinarians, reducing the need for expensive specialized scans and consultations with cardiologists.

Promising Results and Future Implications

The algorithm’s performance was encouraging: it aligned with cardiologists’ assessments in over half of the cases, and in 90% of instances, it was within one grading unit of the cardiologist’s evaluation. Dr. McDonald pointed out the practical implications of these findings: “The grade of heart murmur is a useful differentiator for determining next steps and treatments, and we’ve automated that process.”

Novo Matos remarked on the transformative potential of this technology, seeing it as a supportive tool rather than a job threat. “So many people talk about AI as a threat to jobs, but for me, I see it as a tool that will make me a better cardiologist,” he said. With the veterinary profession facing time constraints and a shortage of specialists, this algorithm could streamline the process of identifying dogs that need urgent care.

A Path Forward for Veterinary Medicine

The researchers’ ultimate goal is to equip veterinarians with the means to make informed decisions regarding treatment, enhancing the quality of life for their canine patients. “Knowing when to medicate is so important, in order to give dogs the best quality of life possible for as long as possible,” said Agarwal.

Supported by organisations such as the Kennel Club Charitable Trust and the Medical Research Council, this research marks a significant step forward in the use of machine learning for veterinary applications. As technology continues to evolve, it holds the promise of not only advancing animal health but also improving the human-animal bond through better care and understanding.

EP Staff is the editorial team at EdPublica, an independent media organisation focused on science, education, environment and public policy. The team produces evidence-based news, features, explainers and analysis on issues that shape society and everyday life.

The Sciences

MIT Researchers Develop Origami-Based Method for Lightweight, Load-Bearing Structures

MIT researchers have developed an origami-inspired construction technique that could enable lightweight, rigid structures using less material and simpler assembly methods.

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Folded aluminium geometric structure displayed in a public library atrium, demonstrating an origami-inspired architectural design.
MIT researchers have developed an origami-inspired construction technique that could enable lightweight, rigid structures using less material and simpler assembly methods.Image credit:MIT

Researchers at the Massachusetts Institute of Technology (MIT) have developed an origami-inspired construction method that could enable the fabrication of lightweight, rigid structures using less material and simpler assembly techniques. The approach could eventually be used for emergency shelters, architectural components and lightweight aerospace parts.

The modular system uses components cut from flat sheets of material, folded into shape and connected to form three-dimensional structural shells. According to MIT, simulations indicate that the structures can be approximately 3.5 times stiffer than those produced using some other structural origami techniques, while requiring only about two-thirds as much material.The research was announced by MIT on October 27 and published in the International Journal of Solids and Structures.

Building structures through folding

The researchers drew inspiration from geometric patterns developed by artist and scientist Ron Resch in the 1960s. Unlike methods that fold a single sheet into a complete structure, the new approach uses individually fabricated components that are folded and connected to create a larger framework.

Alfonso Parra Rubio, a graduate student at MIT’s Center for Bits and Atoms and lead author of the study, developed a method for combining two tripod-shaped units into a rigid building block. These blocks can be interconnected to form a network of beams that creates a lightweight structural shell.

To simplify the design process, the team developed computational software that automatically generates components according to the intended structure. The software checks whether individual units can be folded before combining them into the final design.

The resulting files can be sent to computer-controlled cutting equipment to manufacture components from flat sheets of material, including aluminium. Workers can then fold and assemble the units using basic hand tools, without requiring large-scale welding equipment.

Demonstration at architectural scale

To demonstrate the method’s scalability, the researchers constructed a 23-foot folded-aluminium sculpture that was installed in the atrium of the Boston Public Library. According to MIT, a team without professional construction experience assembled the structure in a matter of days.

The researchers say the modular design simplifies assembly because the components are engineered to fit into their intended positions as the structure takes shape.

Untitled design 39 1

Representational image.Image credit:Pexels

However, the reported stiffness improvements are based on simulations comparing the method with other origami-based systems. Further testing will be necessary to establish its performance across different materials, loading conditions and real-world construction environments.

Potential applications

One potential application is disaster-relief housing. Flat-packed components could be transported efficiently to areas affected by earthquakes or floods and assembled on site, potentially reducing transportation and construction requirements.

The approach could also be explored for lightweight aerospace components, modular robots, sound-dampening panels and building facades. Its ability to create rigid structural shells without interior support columns could offer additional flexibility in architectural design.

The researchers plan to test the technique in larger architectural structures and investigate more complex component geometries that could improve strength and stiffness. They also intend to develop a more accessible interface for designing structures using the system.

While the method has yet to demonstrate widespread use in buildings, the research illustrates how geometric design and digital manufacturing could offer alternatives for constructing complex structures.

Its practical adoption will depend on factors including durability, manufacturing costs, structural safety and performance under real-world conditions. Nevertheless, the approach presents a potential option for applications where reducing material use and simplifying assembly are priorities.

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Space & Physics

Indian-Belgian Team Develops Portable Detectors to Image Mountains and Monuments Using Cosmic Rays

Portable cosmic-ray detectors could help researchers examine mountains, tunnels and historical monuments without invasive procedures, opening new possibilities for scientific imaging and infrastructure inspection.

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Computer monitor displaying cosmic-ray particle tracks in a physics laboratory.
A particle detector displays tracks produced by cosmic rays, illustrating how scientists study high-energy particles for non-invasive imaging applications.Image credit:Pexels

An international team of researchers from India and Belgium has developed portable particle detectors that could help scientists examine the interiors of mountains, tunnels and historical monuments without damaging them. The technology uses naturally occurring cosmic-ray particles to map variations in the density of objects, offering a potential approach to non-invasive imaging of large structures.

The detectors, developed using glass-based Resistive Plate Chambers (RPCs), achieved a particle-detection efficiency exceeding 95% during testing, according to a report published by Research Matters on October 24, 2026. The findings demonstrate the potential of compact detector systems to investigate dense materials and support future applications in geology, archaeology and infrastructure assessment.

The collaboration includes researchers from India’s National Institute of Science Education and Research (NISER), Bhubaneswar, and the Homi Bhabha National Institute (HBNI), alongside researchers from Belgian institutions, including Université catholique de Louvain and the Inter-University Institute for High Energies.

How cosmic rays reveal hidden structures

The technology uses muons, high-energy particles produced when cosmic rays interact with Earth’s atmosphere. These particles continuously reach the Earth’s surface and can penetrate substantial thicknesses of rock, concrete and other materials.

As muons travel through an object, some are absorbed or deflected depending on its density and thickness. By measuring the number and trajectories of particles passing through a structure, researchers can identify variations in internal density and reconstruct images of otherwise inaccessible areas.

The technique, known as muography, is comparable in principle to X-ray imaging, but uses naturally occurring particles instead of an artificial radiation source. It has previously been used to investigate geological formations, including volcanoes, and to explore archaeological structures.

However, conventional muon detectors can be bulky, difficult to transport and challenging to operate in remote locations. The new glass-based detectors aim to address some of these limitations through a compact design and sealed operation, reducing dependence on continuous gas supplies.

Testing the detector system

The researchers developed three glass RPC prototypes using thin glass electrodes separated by gas-filled gaps. When a muon passes through a chamber, it ionises the gas, generating an electrical signal that can be recorded to determine the particle’s position.

Electronic readout systems capture these signals and help reconstruct the trajectories of incoming particles. During testing, the detectors achieved an efficiency exceeding 95%, with a timing resolution of approximately 1.8 nanoseconds, according to the research report.

To examine the system’s ability to detect dense materials, the team conducted an absorption experiment using one prototype. During an open-sky measurement, researchers recorded nearly 55,000 muon tracks. After placing a lead block in the experimental setup, the recorded count fell to 30,894, demonstrating how dense material reduced the number of particles reaching the detector.

detectors
cosmic rays

Representational image.Image credit:Pexels

The experiment provided proof of principle that the system could measure muon attenuation and support radiographic imaging. However, imaging complex structures such as mountains or monuments requires measurements from multiple directions and further computational reconstruction.

Applications and challenges ahead

Portable muon detectors could eventually help researchers investigate hidden cavities, examine geological formations, inspect tunnels and study the internal structures of historical monuments. Engineers could also explore their application in assessing infrastructure such as dams and bridges, although these uses would require additional testing and validation.

For cultural heritage conservation, muography could offer a valuable alternative where drilling or other invasive investigations risk damaging fragile structures. A 2025 review published in iScience highlighted the technique’s potential as a complementary, non-destructive method for studying cultural heritage objects, while noting that the relatively low flux of naturally occurring muons can require lengthy data-collection periods.

The technology is not yet a universal replacement for existing inspection methods. Its practical application will depend on factors such as spatial resolution, detector size, measurement duration and the complexity of the structure being examined.

The researchers have proposed further improvements, including lighter structural materials, larger detector areas and enhanced readout systems. These developments could make the detectors easier to deploy and improve the quality of reconstructed images.

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Technology

Thorium-229 Nuclear Clock Opens New Way to Probe Dark Matter

Scientists have demonstrated a working thorium-229 nuclear clock, opening new possibilities for precision timekeeping and research into dark matter.

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Scientific illustration of a thorium atom showing its nucleus at the centre and electrons arranged in concentric shells.
An illustration of a thorium atom. Researchers are studying the thorium-229 isotope to develop nuclear clocks that could advance precision timekeeping and tests of fundamental physics.Image credit:Pixabay

Scientists have demonstrated a working nuclear clock based on thorium-229, an advance that could open new possibilities for precision timekeeping and the search for dark matter. Unlike conventional atomic clocks, which measure transitions involving electrons, the device uses an energy transition inside an atomic nucleus. The clock operates with thorium-229 nuclei embedded in a small crystal at room temperature, offering a potential route towards compact and highly sensitive timekeeping technology.

The findings, published in Nature demonstrate how a laser can be continuously stabilised using the nuclear transition itself. The researchers also used the device to investigate whether dark matter might produce detectable changes in fundamental physical quantities.

From atomic transitions to the atomic nucleus

Modern atomic clocks measure the frequency of radiation associated with transitions between energy levels in atoms or ions. Because these frequencies are highly stable, they provide precise standards for measuring time and testing physical theories.

The proposed nuclear clock uses thorium-229, an isotope with an unusually low-energy nuclear transition that can be excited using ultraviolet light. Researchers have explored this possibility for decades because nuclear transitions are expected to be less sensitive to some external disturbances than electronic transitions.

In the new experiment, the researchers embedded thorium-229 nuclei in a millimetre-sized calcium fluoride crystal. The device operated at approximately room temperature, around 294.7 kelvin. A laser emitting radiation at a wavelength of 148 nanometres was used to probe the nuclear transition.

A central feature of the experiment was its feedback system. The researchers measured how much laser light the nuclei absorbed and used the resulting signal to correct the laser frequency. This allowed the nuclear transition to serve as the reference for stabilising the laser, rather than relying entirely on an external reference.

Ytterbium Optical Lattice Clock purple and green light

A ytterbium optical lattice clock at NMIJ, National Metrology Institute of Japan used to measure International Atomic Time (TAI).Image credi:Wikimedia commons

The team also compared the nuclear clock with an established ytterbium-ion optical clock. This comparison helped researchers assess the new device’s frequency stability and look for possible changes in the thorium transition.

A new tool in the search for dark matter

Beyond timekeeping, the clock offers a way to investigate possible changes in fundamental constants of nature. Some theoretical models propose that ultralight dark matter could cause these constants to vary over time, producing small changes in the frequencies measured by precision clocks.

The researchers compared the thorium clock’s frequency with that of the ytterbium reference over approximately 23 hours. They searched for periodic fluctuations and gradual drifts that could indicate such changes.

The experiment found no statistically significant periodic signal within the range examined. Instead, the measurements placed new limits on certain interactions between ultralight dark matter and ordinary matter. The resulting constraints were competitive with leading atomic-clock measurements for some photon-related interactions and improved previous constraints involving the strong nuclear force.

These results do not establish the existence of dark matter, nor do they rule out all possible models. They demonstrate how a nuclear clock can be used to test predictions that might otherwise be difficult to investigate experimentally.

Challenges remain

The device is still a developing technology. Its performance is limited by factors including laser power, measurement noise and variations in the crystal’s nuclear transition frequency at different locations. The researchers also identified reproducibility between measurements taken on different days as an important limitation.

They suggest that stronger ultraviolet laser sources and improvements to the crystal material could substantially improve the clock’s stability and sensitivity. Their projections indicate that future versions could approach the performance of leading optical atomic clocks while retaining the practical advantages of a solid-state system.

The demonstration marks a significant step towards nuclear clocks that can operate as standalone devices. Further improvements will determine how effectively the technology can support precision timekeeping and searches for new physics.

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