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Space & Physics

Scientists Use Light to Direct Movement in Starfish Egg Cells

By genetically engineering a light-sensitive version of this enzyme, the researchers were able to use light to direct the cell’s motion in precise patterns

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The study’s senior author, Nikta Fakhri, associate professor of physics at MIT. Credits:Photo: Adam Glanzman

The ability to control the behaviour of individual cells has long been a goal of scientists studying cell development. MIT researchers have now developed a method to manipulate how a single cell moves and changes shape, using light. This breakthrough, which could have far-reaching applications in synthetic biology and medicine, was demonstrated in egg cells from starfish—a common model for understanding cell behaviour during development.

The team, led by Nikta Fakhri, focused on an enzyme within the starfish egg cell that triggers a cascade of movements. By genetically engineering a light-sensitive version of this enzyme, the researchers were able to use light to direct the cell’s motion in precise patterns.

“We found that the light successfully triggered the enzyme, which in turn prompted the cells to jiggle and move in predictable patterns,” says Fakhri, an associate professor of physics at MIT. “For instance, we could stimulate cells to exhibit small pinches or sweeping contractions, depending on the pattern of light we induced. We could even shine light at specific points around a cell to stretch its shape from a circle to a square.”

The findings, set to be published in Nature Physics, open up exciting possibilities for future medical and synthetic cell applications. The researchers envision using this technology to design cells that could respond to light for therapeutic purposes, such as “patch” cells that contract to help close wounds or drug-delivering cells that release medication only when illuminated at specific locations in the body.

Fakhri continues, “By revealing how a light-activated switch can reshape cells in real time, we’re uncovering basic design principles for how living systems self-organize and evolve shape.”

The research team includes MIT’s Jinghui Liu, Yu-Chen Chao, and Tzer Han Tan, alongside collaborators from Ludwig Maximilian University of Munich, Saarland University, and the Whitehead Institute for Biomedical Research.

Exploring the Starfish Model

Fakhri’s group specializes in understanding the physical dynamics that drive cell growth, especially the role of symmetry in cell development. The starfish, known for its distinct stages of symmetry, is an ideal organism for studying the signalling processes that guide cell organization.

“A starfish is fascinating because it starts with a symmetrical cell and eventually develops into an adult with pentameral symmetry,” Fakhri explains. “There are many signalling events along the way that direct how the cell organizes itself into more complex structures.”

The team’s earlier research identified a key “circuitry” in the starfish egg cell that regulates its movement and shape. This circuitry involves an enzyme called GEF, which, when activated, triggers a protein called Rho. Rho plays a crucial role in regulating cell mechanics by binding to the cell’s membrane and initiating the formation of muscle-like fibres that enable the cell to contract and move.

Harnessing Light to Control Cell Movement

In this new study, the team turned to optogenetics, a technique that uses light to control genetically engineered cellular components. They created a light-sensitive version of the GEF enzyme and injected it into egg cells harvested from starfish. The cells, now capable of producing the light-sensitive enzyme, were placed under a microscope, and the researchers applied light in different patterns to observe how the cells responded.

By targeting specific areas of the cell with light, they were able to activate the enzyme, triggering the Rho protein to form fibers and cause the cell to move. This allowed the team to control the cell’s shape, even morphing it from a circle into a square. Additionally, they discovered that shining light in a single spot could initiate sweeping contractions within the cell, providing even more precise control over its behaviour.

“We realized this Rho-GEF circuitry is an excitable system, where a small, well-timed stimulus can trigger a large, all-or-nothing response,” Fakhri says. “By illuminating either the entire cell or just a small region, we can control how the cell responds and causes contraction or pinching.”

The researchers also developed a theoretical framework to predict how cells would change in response to light stimuli. This new understanding of cellular “excitability” could have important implications for fields like developmental biology, wound healing, and synthetic biology.

Future Applications in Synthetic Biology

“This work provides a blueprint for designing programmable synthetic cells,” Fakhri explains. “By controlling cell shape in real time, we can potentially design cells that perform specific tasks in the body when activated by light. This could lead to new biomedical applications, from targeted drug delivery to tissue repair.”

The ability to control cell behaviour with light opens up exciting possibilities for future research and applications, offering a new way to explore how cells shape themselves during development and how we might harness these processes for therapeutic use.

Space & Physics

Physicists Capture ‘Wakes’ Left by Quarks in the Universe’s First Liquid

Scientists at CERN’s Large Hadron Collider have observed, for the first time, fluid-like wakes created by quarks moving through quark–gluon plasma, offering direct evidence that the universe’s earliest matter behaved like a liquid rather than a cloud of free particles.

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Physicists Capture ‘Wakes’ Left by Quarks in the Universe’s First Liquid
Image credit: Jose-Luis Olivares, MIT

Physicists working at the CERN(The European Organization for Nuclear Research) have reported the first direct experimental evidence that quark–gluon plasma—the primordial matter that filled the universe moments after the Big Bang—behaves like a true liquid.

Using heavy-ion collisions at the Large Hadron Collider, researchers recreated the extreme conditions of the early universe and observed that quarks moving through this plasma generate wake-like patterns, similar to ripples trailing a duck across water.

The study, led by physicists from the Massachusetts Institute of Technology, shows that the quark–gluon plasma responds collectively, flowing and splashing rather than scattering randomly.

“It has been a long debate in our field, on whether the plasma should respond to a quark,” said Yen-Jie Lee in a media statement. “Now we see the plasma is incredibly dense, such that it is able to slow down a quark, and produces splashes and swirls like a liquid. So quark-gluon plasma really is a primordial soup.”

Quark–gluon plasma is believed to be the first liquid to have existed in the universe and the hottest ever observed, reaching temperatures of several trillion degrees Celsius. It is also considered a near-perfect liquid, flowing with almost no resistance.

To isolate the wake produced by a single quark, the team developed a new experimental technique. Instead of tracking pairs of quarks and antiquarks—whose effects can overlap—they identified rare collision events that produced a single quark traveling in the opposite direction of a Z boson. Because a Z boson interacts weakly with its surroundings, it acts as a clean marker, allowing scientists to attribute any observed plasma ripples solely to the quark.

“We have figured out a new technique that allows us to see the effects of a single quark in the QGP, through a different pair of particles,” Lee said.

Analysing data from around 13 billion heavy-ion collisions, the researchers identified roughly 2,000 Z-boson events. In these cases, they consistently observed fluid-like swirls in the plasma opposite to the Z boson’s direction—clear signatures of quark-induced wakes.

The results align with theoretical predictions made by MIT physicist Krishna Rajagopal, whose hybrid model suggested that quarks should drag plasma along as they move through it.

“This is something that many of us have argued must be there for a good many years, and that many experiments have looked for,” Rajagopal said.

“We’ve gained the first direct evidence that the quark indeed drags more plasma with it as it travels,” Lee added. “This will enable us to study the properties and behavior of this exotic fluid in unprecedented detail.”

The research was carried out by members of the CMS Collaboration using the Compact Muon Solenoid detector at CERN. The open-access study has been published in the journal Physics Letters B.

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Space & Physics

Why Jupiter Has Eight Polar Storms — and Saturn Only One: MIT Study Offers New Clues

Two giant planets, made of the same elements, display radically different storms at their poles. New research from MIT now suggests that the key to this cosmic mystery lies not in the skies, but deep inside Jupiter and Saturn themselves.

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Why Jupiter Has Eight Polar Storms — and Saturn Only One: MIT Study Offers New Clues
Image Credit: NASA/JPL-Caltech/SwRI/ASI/INAF/JIRAM

For decades, spacecraft images of Jupiter and Saturn have puzzled planetary scientists. Despite being similar in size and composition, the two gas giants display dramatically different weather systems at their poles. Jupiter hosts a striking formation: a central polar vortex encircled by eight massive storms, resembling a rotating crown. Saturn, by contrast, is capped by a single enormous cyclone, shaped like a near-perfect hexagon.

Now, researchers at the Massachusetts Institute of Technology believe they have identified a key reason behind this cosmic contrast — and the answer may lie deep beneath the planets’ cloud tops.

In a new study published in the Proceedings of the National Academy of Sciences, the MIT team suggests that the structure of a planet’s interior — specifically, how “soft” or “hard” the base of a vortex is — determines whether polar storms merge into one giant system or remain as multiple smaller vortices.

“Our study shows that, depending on the interior properties and the softness of the bottom of the vortex, this will influence the kind of fluid pattern you observe at the surface,” says study author Wanying Kang, assistant professor in MIT’s Department of Earth, Atmospheric and Planetary Sciences (EAPS) in a media release issued by the institute. “I don’t think anyone’s made this connection between the surface fluid pattern and the interior properties of these planets. One possible scenario could be that Saturn has a harder bottom than Jupiter.”

A long-standing planetary mystery

The contrast has been visible for years thanks to two landmark NASA missions. The Juno spacecraft, which has been orbiting Jupiter since 2016, revealed a dramatic polar arrangement of swirling storms, each roughly 3,000 miles wide — nearly half the diameter of Earth. Cassini, which orbited Saturn for 13 years before its mission ended in 2017, documented the planet’s iconic hexagonal polar vortex, stretching nearly 18,000 miles across.

“People have spent a lot of time deciphering the differences between Jupiter and Saturn,” says Jiaru Shi, the study’s first author and an MIT graduate student. “The planets are about the same size and are both made mostly of hydrogen and helium. It’s unclear why their polar vortices are so different.”

Simulating storms on gas giants

To tackle the question, the researchers turned to computer simulations. They created a two-dimensional model of atmospheric flow designed to mimic how storms might evolve on a rapidly rotating gas giant.

While real planetary vortices are three-dimensional, the team argued that Jupiter’s and Saturn’s fast spin simplifies the physics. “In a fast-rotating system, fluid motion tends to be uniform along the rotating axis,” Kang explains. “So, we were motivated by this idea that we can reduce a 3D dynamical problem to a 2D problem because the fluid pattern does not change in 3D. This makes the problem hundreds of times faster and cheaper to simulate and study.”

The model allowed the scientists to test thousands of possible planetary conditions, varying factors such as rotation rate, internal heating, planet size and — crucially — the density of material beneath the vortices. Each simulation began with random chaotic motion and tracked how storms evolved over time.

The outcomes consistently fell into two categories: either the system developed one dominant polar vortex, like Saturn, or several coexisting vortices, like Jupiter.

The decisive factor turned out to be how much a vortex could grow before being constrained by the properties of the layers beneath it.

When the lower layers were made of softer, lighter material, individual vortices could not expand indefinitely. Instead, they stabilized at smaller sizes, allowing multiple storms to coexist at the pole. This matches what scientists observe on Jupiter.

But when the simulated vortex base was denser and more rigid, vortices were able to grow larger and eventually merge. The end result was a single, planet-scale storm — remarkably similar to Saturn’s massive polar cyclone.

“This equation has been used in many contexts, including to model midlatitude cyclones on Earth,” Kang says. “We adapted the equation to the polar regions of Jupiter and Saturn.”

The findings suggest that Saturn’s interior may contain heavier elements or more condensed material than Jupiter’s, giving its atmospheric vortices a firmer foundation to build upon.

“What we see from the surface, the fluid pattern on Jupiter and Saturn, may tell us something about the interior, like how soft the bottom is,” Shi says. “And that is important because maybe beneath Saturn’s surface, the interior is more metal-enriched and has more condensable material which allows it to provide stronger stratification than Jupiter. This would add to our understanding of these gas giants.”

Reading the interiors from the skies

Planetary scientists have long struggled to infer the internal structures of gas giants, where pressures and temperatures are far beyond what can be reproduced in laboratories. This new work offers a rare bridge between visible atmospheric patterns and hidden planetary composition.

Beyond explaining two of the Solar System’s most visually striking storms, the research could shape how scientists interpret observations of distant exoplanets as well — worlds where atmospheric patterns might be the only clues to what lies within.

For now, Jupiter’s swirling crown of storms and Saturn’s solitary hexagon may be doing more than decorating the poles of two distant giants. They may be quietly revealing the deep, unseen architecture of the planets themselves.

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Space & Physics

When Quantum Rules Break: How Magnetism and Superconductivity May Finally Coexist

A new theoretical breakthrough from MIT suggests that exotic quantum particles known as anyons could reconcile a long-standing paradox in physics, opening a path to an entirely new form of superconductivity.

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When Quantum Rules Break: How Magnetism and Superconductivity May Finally Coexist
Image credit: Pawel Czerwinski/UnSplash

For decades, physicists believed that superconductivity and magnetism were fundamentally incompatible. Superconductivity is fragile: even a weak magnetic field can disrupt the delicate pairing of electrons that allows electrical current to flow without resistance. Magnetism, by its very nature, should destroy superconductivity.

And yet, in the past year, two independent experiments upended this assumption.

In two different quantum materials, researchers observed something that should not have existed at all: superconductivity and magnetism appearing side by side. One experiment involved rhombohedral graphene, while another focused on the layered crystal molybdenum ditelluride (MoTe₂). The findings stunned the condensed-matter physics community and reopened a fundamental question—how is this even possible?

Now, a new theoretical study from physicists at the Massachusetts Institute of Technology offers a compelling explanation. Writing in the Proceedings of the National Academy of Sciences, the researchers propose that under the right conditions, electrons in certain magnetic materials can split into fractional quasiparticles known as anyons—and that these anyons, rather than electrons, may be responsible for superconductivity.

If confirmed, the work would introduce a completely new form of superconductivity, one that survives magnetism and is driven by exotic quantum particles instead of ordinary electrons.

“Many more experiments are needed before one can declare victory,” said Senthil Todadri, William and Emma Rogers Professor of Physics at MIT, in a media statement. “But this theory is very promising and shows that there can be new ways in which the phenomenon of superconductivity can arise.”

A Quantum Contradiction Comes Alive

Superconductivity and magnetism are collective quantum states born from the behavior of electrons. In magnets, electrons align their spins, producing a macroscopic magnetic field. In superconductors, electrons pair up into so-called Cooper pairs, allowing current to flow without energy loss.

For decades, textbooks taught that the two states repel each other. But earlier this year, that belief cracked.

At MIT, physicist Long Ju and colleagues reported superconductivity coexisting with magnetism in rhombohedral graphene—four to five stacked graphene layers arranged in a specific crystal structure.

“It was electrifying,” Todadri recalled in a media statement. “It set the place alive. And it introduced more questions as to how this could be possible.”

Soon after, another team reported a similar duality in MoTe₂. Crucially, MoTe₂ also exhibits an exotic quantum phenomenon known as the fractional quantum anomalous Hall (FQAH) effect, in which electrons behave as if they split into fractions of themselves.

Those fractional entities are anyons.

Meet the Anyons: Where “Anything Goes”

Anyons occupy a strange middle ground in the quantum world. Unlike bosons, which happily clump together, or fermions, which avoid one another, anyons follow their own rules—and exist only in two-dimensional systems.

First predicted in the 1980s and named by MIT physicist Frank Wilczek, anyons earned their name as a playful nod to their unconventional behavior: anything goes.

Decades ago, theorists speculated that anyons might be able to superconduct in magnetic environments. But because superconductivity and magnetism were believed to be mutually exclusive, the idea was largely abandoned.

The recent MoTe₂ experiments changed that calculus.

“People knew that magnetism was usually needed to get anyons to superconduct,” Todadri said in a media statement. “But superconductivity and magnetism typically do not occur together. So then they discarded the idea.”

Now, Todadri and MIT graduate student Zhengyan Darius Shi, co-author of the study, revisited the old theory—armed with new experimental clues.

Using quantum field theory, the team modeled how electrons fractionalize in MoTe₂ under FQAH conditions. Their calculations revealed that electrons can split into anyons carrying either one-third or two-thirds of an electron’s charge.

That distinction turned out to be critical.

Anyons are notoriously “frustrated” particles—quantum effects prevent them from moving freely together.

“When you have anyons in the system, what happens is each anyon may try to move, but it’s frustrated by the presence of other anyons,” Todadri explained in a media statement. “This frustration happens even if the anyons are extremely far away from each other.”

But when the system is dominated by two-thirds-charge anyons, the frustration breaks down. Under these conditions, the anyons begin to move collectively—forming a supercurrent without resistance.

“These anyons break out of their frustration and can move without friction,” Todadri said. “The amazing thing is, this is an entirely different mechanism by which a superconductor can form.”

The team also predicts a distinctive experimental signature: swirling supercurrents that spontaneously emerge in random regions of the material—unlike anything seen in conventional superconductors.

Why This Matters Beyond Physics

If experiments confirm superconducting anyons, the implications could extend far beyond fundamental physics.

Because anyons are inherently robust against environmental disturbances, they are considered prime candidates for building stable quantum bits, or qubits—the foundation of future quantum computers.

“These theoretical ideas, if they pan out, could make this dream one tiny step within reach,” Todadri said.

More broadly, the work hints at an entirely new category of matter.

“If our anyon-based explanation is what is happening in MoTe₂, it opens the door to the study of a new kind of quantum matter which may be called ‘anyonic quantum matter,’” Todadri said. “This will be a new chapter in quantum physics.”

For now, the theory awaits experimental confirmation. But one thing is already clear: a rule long thought unbreakable in quantum physics may no longer hold—and the quantum world just became a little stranger, and far more exciting.

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