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How a South African Hospital Team Pioneered the World’s First AI-Powered Cancer Treatment Revolution

Digital Healing: How Bloemfontein Became Ground Zero for the AI Cancer Treatment Revolution

Joe Jacob

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Illustrative image for representative purpose/EdPublica

The University of the Free State (UFS), South Africa, and Universitas Academic Hospital have achieved a global healthcare milestone by becoming the first clinical site worldwide to successfully integrate artificial intelligence into cancer treatment planning, marking a transformative advancement in oncology care, according to a statement issued by UFS.

AI implementation

The Departments of Medical Physics and Oncology at UFS, in partnership with Universitas Academic Hospital, have implemented the Radiation Planning Assistant (RPA), a sophisticated web-based AI platform developed by MD Anderson Cancer Center in Houston, Texas. This pioneering initiative has already treated nearly 50 patients, positioning the Bloemfontein-based teams as global leaders in the clinical application of AI in radiotherapy.

Under the leadership of Dr. William Shaw, Senior Lecturer and Deputy Manager in the Department of Medical Physics, the institution has built a robust academic partnership with Professor Laurence Court and his team at MD Anderson Cancer Center—a collaboration that is now yielding remarkable real-world results.

“The introduction and clinical integration of the RPA at the UFS and Universitas Hospital represents a major advancement for oncology services—both regionally and nationally,” Dr. Shaw explained. “It signifies the transition from research collaboration to real-world application, where artificial intelligence is being used to improve access to safe, high-quality cancer care.”

Revolutionizing treatment planning

The RPA technology addresses one of the most time-consuming aspects of cancer care: creating patient-specific radiation treatment plans. The cloud-based platform automates critical components of the treatment planning process, enabling consistent production of high-quality radiotherapy plans while reducing demands on specialized clinical staff.

Dr. Shaw described the streamlined process: “The process begins with the acquisition of a planning CT scan, which serves as the sole imaging input to the RPA. Once the CT dataset has been captured, it is uploaded to the RPA platform via a secure web interface.”

The system uses advanced machine learning algorithms to automatically identify and delineate both tumour volumes and critical normal tissues. Following the completion of the contouring process, the platform automatically generates a comprehensive radiotherapy treatment plan.

Expanding treatment applications

Initially implemented for cervix cancer treatment—representing the largest proportion of radiotherapy patients at the institution—the RPA has since expanded to encompass breast cancer, head and neck cancers, and primary brain tumors. With ongoing institutional support, the system shows significant promise for broader application across nearly all major tumor types treated with external beam radiotherapy.

Professor Vasu Reddy, Deputy Vice-Chancellor for Research and Internationalisation at UFS, praised the achievement: “We extend our congratulations to our colleagues for their exemplary collaborative achievements. Your pioneering work represents the transformative power of multidisciplinary research in advancing medical science and improving patient outcomes.”

Immediate patient benefits

The technology delivers immediate, meaningful improvements for cancer patients by enabling faster access to well-constructed, evidence-based treatment plans reviewed and refined by experts. This translates to more timely care, fewer unplanned treatment interruptions, and improved protection of normal tissues, resulting in fewer side effects and better overall outcomes.

“Our aim is to use artificial intelligence not as a shortcut, but as a tool to standardize, scale, and improve cancer care in places where the need is greatest,” Dr. Shaw emphasized. “The RPA enhances the quality, consistency, and timeliness of cancer treatment in radiotherapy settings—particularly in environments where clinical capacity is limited.”

International expansion

The success in Bloemfontein serves as a model for broader health system innovation, providing a foundation for the safe, phased rollout of similar systems in other provinces. Professor Court has already extended access to the RPA to other radiotherapy centers in South Africa, with expansion to additional countries planned for the near future.

The Department of Oncology, led by Professor Alicia Sherriff, has joined the initiative as an active clinical partner, establishing a multi-disciplinary collaboration that lays the foundation for further research and innovation at the intersection of medical physics, oncology, and data science.

Advanced treatment techniques

Beyond external beam radiotherapy, the UFS and Universitas teams are advancing the use of interstitial brachytherapy for cervix cancer. While not the first globally to implement this specialized technique, the Bloemfontein team ranks among the earliest adopters on the African continent, helping expand access to this advanced modality where it’s most needed.

Future vision

This work received support from the Nuclear Technologies in Medicine and the Biosciences Initiative (NTeMBI), a national technology platform developed and managed by the South African Nuclear Energy Corporation (Necsa) and funded by the Technology Innovation Agency (TIA).

Dr. Shaw’s team has played a central role in developing safe, reliable clinical processes to integrate AI tools like the RPA into daily practice, ensuring that automation enhances rather than replaces professional expertise.

Professor Reddy outlined the broader vision, “The future we are heading towards is one where human innovation and digital technologies work together to elevate the standard of care, rather than replace humanity in medicine. It is encouraging to see how our colleagues are internationalizing our footprint, together with machine precision to enhance detection, personalize treatment and, perhaps importantly, empowering clinicians with data-driven insights for patient care.”

This innovation represents a significant step forward for cancer care in South Africa and demonstrates how international partnerships can bring cutting-edge technologies to healthcare frontlines, making them work effectively in real clinics for real patients. As cancer incidence rises across low- and middle-income countries, the leadership shown by the UFS and Universitas teams offers a compelling model for how academic medical centers can respond with agility, scientific rigor, and global solidarity.

Edited by Chris Jose

Health

FSSAI Moves to Restrict Added Sugars in Infant Foods, Citing Need for Stronger Nutritional Safeguards

FSSAI has proposed restricting the addition of sucrose and fructose to infant foods for babies up to six months. The draft amendment aims to strengthen nutritional safeguards.

Vaishnavi V S

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Mother feeding a newborn baby with a spoon, illustrating concerns around infant nutrition and feeding practices.
FSSAI has proposed prohibiting the addition of sucrose and fructose to food products intended for infants up to six months of age. Representational image. Image credit: Pragyan Bezbaruah/ Pexels

The first months of life leave little room for nutritional guesswork. An infant’s food must supply the energy and nutrients needed for growth, making the composition of commercial infant nutrition products a matter of public health. Whether manufacturers need to add particular sugars to these products is therefore an important regulatory question.

Research published in recent years has begun examining how added sugars enter infants’ diets, including through formula milk, and whether early exposure is associated with subsequent eating patterns and weight gain. Although the evidence does not establish that added sucrose or fructose in infant formula directly causes obesity, it has raised questions about the nutritional value of adding sugars when alternative carbohydrate sources are available.

Against this backdrop, the Food Safety and Standards Authority of India (FSSAI) has proposed prohibiting the addition of sucrose and fructose to food products intended for infants up to six months of age. The draft amendment, published in the Gazette of India on 16 October 2026, would tighten the existing rules governing the composition of these products.

Early Exposure to Added Sugars

An Indian study published in the Indian Journal of Community Medicine in 2021 examined the sugar and salt content of 114 commercially available infant formulas and baby foods. The researchers found that around 28% of the products had a high-sugar profile, while approximately 51% listed sugar or related ingredients among their first four ingredients.

The study covered products intended for children aged up to 24 months, including infant formulas and complementary foods. Its findings offer evidence that sugar content warrants scrutiny in India’s infant and young-child food market. However, the assessment relied on product labels and did not establish whether the products caused adverse health outcomes. It also did not demonstrate that infant formulas intended specifically for babies under six months routinely contained added sucrose or fructose.

Research elsewhere has examined possible links between added sugars in infant formula and early growth. A 2025 study published in The Journal of Nutrition followed 234 infants from predominantly low-income households in the United States. Researchers assessed dietary intake at six, nine and 12 months and found an association between higher added-sugar intake from formula and higher weight-for-length scores.

For every additional 10 grams of added sugar consumed daily through formula, weight-for-length scores increased by an average of 0.060. The study was observational, so it cannot establish that sugar caused the difference. Its findings also cannot be directly generalised to Indian infants.

A separate study published in Frontiers in Nutrition in 2023 examined dietary data from 95 infants and toddlers aged nine to under 16 months. It found an association between added sugars consumed through infant formula and sugar-sweetened beverage consumption later in infancy. The researchers did not establish a significant association between formula-derived added sugars and added-sugar intake from table foods. The small sample and cross-sectional design limit the conclusions that can be drawn.

These studies examine different aspects of early sugar exposure: the composition of products available in India, associations with infant weight and possible links with later dietary patterns. None establishes that the proposed restriction will prevent childhood obesity. They do, however, provide grounds for examining whether particular sugars need to be added to products intended for very young infants.

Infant’s Food: Why the First Six Months Matter

The World Health Organization (WHO) and UNICEF recommend exclusive breastfeeding during the first six months of life, followed by the introduction of appropriate complementary foods at around six months while breastfeeding continues.

Infant's food: Infant drinking milk from a feeding bottle held by an adult.
FSSAI has proposed restricting the addition of sucrose and fructose to food products intended for infants up to six months, as part of efforts to strengthen infant nutrition standards in India. Representational image. Image credit: hartono subagio/ Pexels

For infants who require an alternative to breast milk, appropriately formulated infant formula can provide essential nutrition. Its carbohydrate composition must meet nutritional requirements for growth and development. The question for regulators is whether adding particular sugars serves a necessary nutritional purpose in products designed for this age group.

WHO’s 2023 guideline on complementary feeding recommends that children aged six to 23 months should not consume foods high in sugar, salt and trans fats. Its evidence review identified associations between sugar-sweetened beverage consumption during infancy and later obesity in some studies, although the certainty of the evidence was low. The recommendation concerns the broader diet of children aged six months and older; it does not specifically establish the effects of sucrose or fructose in infant formula.

The distinction between naturally occurring sugars and added sugars is equally important. Milk naturally contains lactose, which provides energy. Sucrose and fructose may instead be introduced as ingredients during product formulation. Their use needs to be assessed against the nutritional requirements of the intended age group.

What the FSSAI Amendment Proposes

Under the Food Safety and Standards (Foods for Infant Nutrition) Regulations, 2020, lactose and glucose polymers are the preferred carbohydrate sources in infant nutrition products. The existing rules permit sucrose and/or fructose when required as a carbohydrate source, subject to prescribed limits.

The draft Food Safety and Standards (Foods for Infant Nutrition) Amendment Regulations, 2026, proposes prohibiting the addition of sucrose and fructose to products intended for infants up to six months of age. This would remove the existing allowance for these two sugars in products for this age group. FSSAI has invited objections and suggestions from stakeholders within 60 days from the date on which copies of the relevant Gazette notification are made available to the public. The submissions will be considered before the amendment is finalised.

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NMC Directs Medical Colleges to Set Up Patient Safety Committees

The National Medical Commission has directed medical colleges and medical institutions to establish patient safety committees, designate nodal officers and strengthen procedures to prevent avoidable harm.

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NMC: Medical professionals in protective equipment review documents during a patient safety meeting.
Medical professionals review documents during a meeting, highlighting the importance of coordinated safety practices in healthcare institutions. Representational image. Image credit: Dave Gracia/ Pexels

The National Medical Commission (NMC) has directed medical colleges and medical institutions across India to establish Patient Safety Committees or Cells and designate Patient Safety Nodal Officers to strengthen safety practices and reduce preventable harm in healthcare settings.

The Commission asked the heads of medical institutions to share the composition of their committees and the details of the designated nodal officers with the National Patient Safety Secretariat (NPSS) under the Directorate General of Health Services (DGHS).

The directive follows a communication dated May 8, 2026, from the Additional Director General of Health Services in the Union Ministry of Health and Family Welfare. It seeks to strengthen the adoption of patient safety protocols and standard operating procedures across medical institutions.

NMC’s Multidisciplinary Oversight

The proposed committee will be chaired by the director, head of the institution or medical superintendent. Its membership must include representatives from relevant medical specialties and the patient safety domains identified by the NPSS. Institutions are also advised to designate a nodal officer with sufficient seniority and authority to coordinate safety initiatives.

The framework covers 11 patient safety domains, including medication safety, surgical safety, blood transfusion safety, medical device safety, laboratory and diagnostic safety, infection prevention and control, healthcare-associated infections, antimicrobial resistance, patient and family engagement, vaccine and injection safety, and facility safety. It also encompasses operational research in patient safety and safety in AYUSH services.

The scope extends beyond clinical treatment to areas such as biomedical waste management, fire safety, structural safety and environmental safety. Nursing, hospital administration and other relevant professionals can contribute to the committee’s work.

From Protocols to Institutional Accountability

The directive places responsibility for patient safety within an organised institutional framework. Rather than leaving safety measures to individual departments or healthcare professionals, the proposed mechanism brings clinical, diagnostic and administrative functions under coordinated oversight.

The committee’s terms of reference include reviewing patient safety incidents and near misses, analysing their causes, promoting reporting and recommending corrective and preventive measures. Such reviews can help institutions identify weaknesses in procedures and address risks before they result in further harm.

The effectiveness of these committees will depend on how consistently institutions implement safety protocols, review incidents and act on their findings. Establishing a committee is an administrative step; sustained monitoring and corrective action are essential to translating the framework into safer care.

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World Food Day: India’s Childhood Obesity Burden Raises Concerns Over Diabetes Risk

More than 41 million Indian children and adolescents aged 5–19 were living with overweight or obesity in 2025, according to the World Obesity Atlas 2026. The growing burden raises concerns about long-term health risks, including type 2 diabetes, and highlights the need for healthier food environments, better nutrition and stronger school-based interventions.

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A young boy eating a slice of pepperoni pizza in front of a chain-link fence.
Children’s food environments and dietary habits are increasingly important in discussions about childhood obesity and long-term health risks.Image credit:Pexels

With more than 41 million Indian children and adolescents living with overweight or obesity, experts warn that unhealthy food environments could increase future risks of type 2 diabetes. New national guidance on childhood diabetes and proposed restrictions on junk food sales near schools highlight the need for preventive action.

As the world observes World Food Day on October 16, childhood nutrition is emerging as a challenge that extends beyond hunger and undernutrition. The growing prevalence of overweight and obesity among children is raising concerns about their long-term health, including their risk of developing type 2 diabetes.

India faces a particularly significant challenge. The World Obesity Atlas 2026 estimates that approximately 14.9 million children aged five to nine and 26.4 million children and adolescents aged 10–19 in India were living with overweight or obesity in 2025. Together, these figures amount to more than 41 million young people.

The report also estimates that around 1.39 million Indian children aged five to 19 had hyperglycaemia attributable to high body mass index in 2025. Hyperglycaemia refers to elevated blood glucose levels and is a health indicator associated with metabolic risk; it should not be interpreted as a count of children diagnosed with diabetes.

The figures highlight the importance of addressing childhood obesity early, before associated health risks become more difficult to manage.

Food environments and the risk of early-onset diabetes

The World Health Organization (WHO) reported in September 2026 that 400 million children and adolescents aged five to 19 worldwide were overweight in 2024, including 170 million living with obesity. The prevalence of overweight in this age group increased from 8% in 1990 to 20% in 2024.

Childhood obesity is influenced by a combination of biological, social, economic and environmental factors. Diets high in energy but low in essential nutrients, limited opportunities for physical activity and the easy availability of heavily marketed processed foods can contribute to unhealthy weight gain.

Obesity can increase insulin resistance, in which the body’s cells respond less effectively to insulin. This can raise the risk of type 2 diabetes, a condition that is increasingly important to consider in children and adolescents.

However, the relationship between food and diabetes requires an important distinction. Type 1 diabetes is an autoimmune condition in which the body’s immune system attacks insulin-producing cells in the pancreas. It is not caused by eating sugary foods or being overweight. Type 2 diabetes develops through different mechanisms and is associated with factors including excess body weight, genetics and physical inactivity.

The two conditions require different approaches to prevention and treatment.

India introduces a national childhood diabetes framework

In a significant policy development, the Union Ministry of Health and Family Welfare released a comprehensive guidance document on diabetes mellitus in children on May 3, 2026.

childhood
obesity
diabtetes

Diabetic checkup.Representational image.Image credit:Pexels

The framework outlines a structured approach to screening, diagnosis, treatment and long-term management, linking community-level identification with district hospitals and medical colleges. It also provides for free-of-cost care at public health facilities, including insulin therapy, blood glucose monitoring supplies and follow-up services.

The guidance promotes awareness of the early warning signs of type 1 diabetes through the “4Ts”: Toilet, Thirsty, Tired and Thinner. These refer to frequent urination, excessive thirst, unusual tiredness and unexplained weight loss.

The initiative is important because timely diagnosis and access to insulin can be lifesaving for children with type 1 diabetes. It also highlights the need for health systems to identify and manage diabetes before complications develop.

Schools become a focus of food policy

India is also considering measures to improve the food environments surrounding schools. A Reuters report published on September 24, 2026, said the country was moving towards restrictions on the sale of foods high in fat, salt and sugar within a 50-metre radius of schools.

The proposed measures would affect vendors and shops selling products such as sugary drinks and packaged snacks near educational institutions. The proposal reflects growing concern about the availability of unhealthy foods in places where children spend much of their day.

If implemented effectively, school-focused measures could form part of a wider strategy that includes healthier school meals, accessible drinking water, nutrition education, physical activity and clearer food labelling.

However, restrictions alone cannot address the problem. Families also need affordable access to fruits, vegetables, pulses and other nutritious foods. Public-health measures must account for household budgets and the realities of food access in different communities.

Beyond calories

World Food Day 2026, themed “Innovate today. Nourish tomorrow,” offers an opportunity to reconsider what food security means for children. Access to sufficient calories is essential, but the nutritional quality of food also matters.

Reducing the future burden of type 2 diabetes requires action across healthcare, education, food policy and community environments. At the same time, children living with type 1 diabetes need timely diagnosis, uninterrupted insulin supplies and long-term medical support

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